The two-month strike has forced the suspension of numerous television series as well as the postponement of work on several Hollywood films.
Hollywood has been abuzz with speculation in recent weeks over how the strike may impact the myriad awards shows leading up to and including the Oscars on February 24.
The WGA confirmed on Wednesday that the writers union would erect picket lines around the Golden Globes venue at the Beverly Hilton hotel, appearing to rule out any agreement with the show's producers, Dick Clark Productions, allowing for a temporary waiver.
"Dick Clark Productions is a struck company. As previously announced, the Writers Guild will be picketing the Golden Globe Awards," the WGA said.
The writers union had already announced last month that it would not allow guild members to take part at both the Golden Globes and the Oscars.
The prospect of stars having to cross picket lines before they venture onto the Globes red carpet had been unnerving celebrities caught in the crossfire of the acrimonious dispute.
David Cronenberg, the director of gangster drama "Eastern Promises," which has been nominated for best picture at the Golden Globes, said last month he would be uncomfortable breaking ranks with writers.
"It would be very hard for me to cross a WGA picket line," said Cronenberg, a longstanding member of the WGA. "Everybody will have the same problem," he told Daily Variety.
The Los Angeles Times' theenvelope.com has reported that Globes organisers may cancel the televised broadcast of the event if writers picketed in an effort to prevent a public relations disaster.