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A research team at Capital Medical University, Beijing discovered a new type of biological age marker recently and published their findings and research report in the world-leading academic journal Medicine in July.
Researchers proved that the level of G immune globulin's (Ig G) glycosylation can help determine Chinese people's biological age. They collected demographic, biochemical and hematological data by examining indexes of the Chinese Han population and conducted several experiments on the Clin-TOF time-of-flight mass spectrometer, which was invented by Bioyong, a Zhongguancun enterprise.
In addition, the team built a biological age prediction model relying on glycosylation levels, which may contribute to the prevention, diagnosis and treating of diseases.
The research will continue. Its ultimate aim is to find the relation between biological age and Ig G glycosylation levels as well as bodily inflammation and to further determine whether glycosylation levels are a reliable and stable marker of human age.
Wang Wei, leader of the research team, said many geriatric diseases like hypertension and diabetes are becoming more and more general in younger generations. Biological age no longer reflects real health conditions.
He said more and more study have shown that human aging is related to the body's inflammation state, but knowledge of age-related inflammation and the causes of damage to the immune response system is still limited.
