"In the year to October, the exchange has underlined its position as the world's primary listing venue with 22.3 billion pounds ($45.3 billion) raised through IPOs, 96 percent more than the same period in 2005 and more than any other exchange so far this year," the LSE in rejecting the Nasdaq bid.
Katrina Preston, an analyst at Bridgewell Securities, had anticipated that the LSE would reject the offer, arguing that it "does not represent sufficient value compared with trading valuations of rival exchanges."
But Fox-Pitt Kelton analyst Andrew Mitchell said the bid was shrewdly timed following last week's slump in the share price below 13 pounds, and that it would be "difficult for London to defend itself."
Earlier this year, Nasdaq made an offer of 9.50 pounds per share for the LSE, but abruptly withdrew in March.
Australia's Macquarie Bank Ltd., Germany's Deutsche Bourse AG and Sweden's OM Gruppen have all failed in previous overtures to take over Europe's oldest exchange.
Mitchell said Nasdaq has no obvious rivals this time around.
"Deutsche Boerse attempted before at a much lower level and you can't rule them out entirely, but they are an unlikely candidate," he said.
The New York Stock Exchange owner, NYSE Group Inc., agreed in June to pay $9.96 billion for Euronext, which operates the Paris, Amsterdam, Brussels and Lisbon exchanges. The bid subsequently rose to $13 billion.
The combined sales of Nasdaq and LSE would be about $1.4 billion, based on their last set of full-year results. That compares with about $2.3 billion for NYSE-Euronext.
Nasdaq's Greifeld said he wasn't concerned about last week's news that seven major investment banks _ Citigroup Inc., Credit Suisse Group, Deutsche Bank AG, Goldman Sachs Group Inc., Merrill Lynch & Co., Morgan Stanley and UBS AG _ plan to launch their own European equities exchange next year.
"It's important to note that Nasdaq was not born through a historical monopoly. It has had to compete. We clearly have our competitive instincts engaged," Greifeld told reporters.
Greifeld said Nasdaq would cut transaction fees as trading volumes rise.
"That will be a hallmark of the combined entity," he said.
Analyst David Buik of Cantor Index said the investment banks' plan was a strong reason for a Nasdaq-LSE tie-up.
"The ramifications of dismissing Nasdaq's overtures could be serious," Buik said, adding that bourses must cut their fees to remain competitive.