COVID-19
Latest discoveries

Chinese inactivated vaccines effective against COVID-19 in phase-3 human trials: study

Xinhua | Updated: 2021-05-27 13:35
A staff member takes out samples of the COVID-19 inactivated vaccine at a vaccine production plant of Sinopharm in Beijing, on April 11, 2020. [Photo/Xinhua]

BEIJING -- Two inactivated vaccines developed by the Chinese pharmaceutical giant Sinopharm have shown to be safe and effective against COVID-19 in phase-3 human trials, according to a study published this week in The Journal of the American Medical Association.

The randomized, double-blind and placebo-controlled trials were designed by the Wuhan Institute of Biological Products Co, Ltd, and the Beijing Institute of Biological Products Co, Ltd, both of which belong to the China National Biotec Group(CNBG), affiliated with Sinopharm.

It is the world's first published phase-3 study results of inactivated COVID-19 vaccines, the CNBG said in a statement on Thursday.

According to the study, more than 40,000 people overseas aged 18 and above were enrolled in the trials. The vaccination procedure included two shots with an interval of 21 days.

The virus strains in the study were isolated from two patients in Wuhan's designated coronavirus-treating Jinyintan Hospital and separately used to develop the two inactivated vaccines.

Fourteen days after inoculation, all vaccine receivers produced high titers of antibodies, and the seroconversion rate of neutralizing antibodies was higher than 99 percent in both vaccine groups, indicating strong immune responses induced by the two vaccines, the study said.

Please feel free to contact us by sending your questions to question@chinadaily.com.cn or commenting on China Daily app. We will ask experts to answer them.

Editor's picks
Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US